3D Printing of Octacalcium Phosphate Bone Substitutes

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3D Printing of Octacalcium Phosphate Bone Substitutes

Biocompatible calcium phosphate ceramic grafts are able of supporting new bone formation in appropriate environment. The major limitation of these materials usage for medical implants is the absence of accessible methods for their patient-specific fabrication. 3D printing methodology is an excellent approach to overcome the limitation supporting effective and fast fabrication of individual comp...

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3D printing of mineral–polymer bone substitutes based on sodium alginate and calcium phosphate

We demonstrate a relatively simple route for three-dimensional (3D) printing of complex-shaped biocompatible structures based on sodium alginate and calcium phosphate (CP) for bone tissue engineering. The fabrication of 3D composite structures was performed through the synthesis of inorganic particles within a biopolymer macromolecular network during 3D printing process. The formation of a new ...

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3d Printing of Calcium Phosphate Cement for Craniofacial Bone Reconstruction

In the current scenario of flexible manufacturing processes, the 3D printing shows up as an alternative to generate individual parts with complex geometries. Moreover, the development of the 3D printing machines, software and parameters allows the manufacture of parts in some materials suitable for implantation. In this way, this study investigates the feasibility of the production of patient-s...

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Histomorphometric Analysis of Newly-formed Bone Using Octacalcium Phosphate and Bone Matrix Gelatin in Rat Tibial Defects

Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...

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An Octacalcium Phosphate Forming Cement

The osteoconductive and possibly osteoinductive characteristics of OCP increased the interest in preparation of bone graft materials that contain OCP in its composition. Calcium phosphate cements (CPCs) were prepared using a mixture of α-tricalcium phosphate (α-TCP) and dicalcium phosphate anhydrous (DCPA), with α-TCP / DCPA molar ratio of 1/1 and distilled water or 0.5 mol / L phosphate aqueou...

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ژورنال

عنوان ژورنال: Frontiers in Bioengineering and Biotechnology

سال: 2015

ISSN: 2296-4185

DOI: 10.3389/fbioe.2015.00081